Information content in the universe cannot be lost. This follows from the rules of quantum mechanics. (Possible exception is black holes , which is debatable, but even there, information conservation likely holds).

It means that in principle , a superintelligence could in the future track down every last scrap of information that made up your wife and resurrent her.

Every cell in your brain is being turned over, so consciousness doesn't depend on specific material properties, but only on the information content. And as I mentioned, ALL the information content is still there (distributed and scattered across many atoms to be sure, and it would take super-human intelligence to retrieve it, but this can in principle be done).

In the vastness of space and time , it is highly likely that your wife will at some point live again, as will you.