The Shadowspawn are more like genetic mutations, though, so some of them might survive. Especially the Trollocs and the lesser known ones in The Blight and in other areas of the world.

There will always be bad guys and people with bad motivations, but they won't have access to the powers that come from the supreme evil being, such as True Power, Graymen won't be able to give up their souls for non-descriptiveness, and Fade's will no longer access to a way to make blades.