Personally, I think it should be possible to Unravel the Bore, maybe with Callandor. Basically, the Bore is nothing else than a special, gigantic Gateway drilled with the OP through the Pattern to the DO. We also know from Demandred that one can only sense the Bore in the Pit of Doom, which implies that it is some kind of weave and explains why Rand has to enter the Pit.

If the Bore is such a special Gateway-weave, it should be possible to Unravel it like you can Unravel other weaves (of course this was unknown in the AoL, which explains LTT's failure and Moridin's horror about this discovery). Alviarin demonstrated this in PoD and might provide Rand with a clue. The seals have to vanish (clear the rubble before you can build), because they basically block that the Bore is affected from Randland (while the DO can gradually make the Bore larger, especially by weakening the Pattern through chaos).

It's also interesting that only LTT/Rand and Demandred are able to block a Gateway.

However, I also think that Rand's special blood might somehow literally play a part, because of the Prophecies and since we know that blood can have some effects in the Pit of Doom (e.g. in mindtrapping someone).