I don't personally know any better, but given that one can feel like a man or a woman, and can see the physical morphology, I'd imagine those two points would be the focus. The actual chromosomes, being invisible and unchangeable, are possibly irrelevant re: emotional satisfaction.

Of course. Study it, learn which solutions work best against the main issue for the individual. I strongly disagree that it's a simple yes or no answer for every person struggling with identity. If we treated every diagnosis as though it had one answer, we'd struggle to help the individual appropriately. Some need medicine, some don't. And there are so many methods and permutations of therapy.

I have no skin in the game, but if more people are "saved" from suicide, and are offered healthier (by personal definition) lives through sex-changes, I genuinely don't see how it's any of my business. I wouldn't tell anyone not to get a boob job or other plastic surgery, either, even though I think those things are crazy (for me).